AZD9496 - CAS# 1639042-08-2 Catalog No.:M7101-2 AZD-2281 is applied to SW620

AZD-2281 is applied to SW620 cell lysates

287±16 mm3

It does not inhibit other DUBs or other families of cysteine proteases tested (EC50 > 100 mM)

This agent is used to homodimerize the Fv-containing drug-binding domains of genetically engineered receptors such as the iCD40 receptor of the autologous dendritic cell vaccine BP-GMAX-CD1

TRPM8 antagonist 2 (Compound 14) is a potent and selective TRPM8 antagonist

AZD9496 - CAS# 1639042-08-2 Catalog No.:M7101-2 AZD-2281 is applied to SW620AZD9496, CAS No. 1639042 08 2, is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ER degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer. Product information CAS Number: 1639042 08 2 Molecular Weight: 442. 47 Formula: C25H25F3N2O2 Synonym: AZD9496 AZD 9496 AZD 9496