LDC1267 ole PubMed PMID: 17785584

PubMed PMID: 17785584

ZSTK474 blocks VEGF-induced cell migration and the tube formation in human umbilical vein endothelial cells (HUVECs)

197:138-47

CAS Number: 1246820-62-1

The increasing concentrations of BMS-3 result in a strong decrease on the percentage of sperm that undergoes acrosomal exocytosis after stimulation with 20 μM of Progesterone[2]

LDC1267 ole PubMed PMID: 17785584LDC1267 is a potent and selective TAM kinase inhibitor. LDC1267 displays lower activity against Met, Aurora B, Lck, Src, and CDK8. LDC1267 markedly reduced murine mammary cancer and melanoma metastases dependent on NK cells. The TAM tyrosine kinase receptors Tyro3, Axl and Mer (also known as Mertk) were identified as ubiquitylation substrates for Cbl b. Treatment of wild type NK cells with a newly developed small molecule TAM kinase inhibitor