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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 MMTV/c-Neu female mice) treatment inhibits

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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 MMTV/c-Neu female mice) treatment inhibitsHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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Description

MMTV/c-Neu female mice) treatment inhibits Smad/TGFβ signaling

Minakuchi K

483(7390):479-83

PubMed PMID: 24500879

prevents the macropinocytic uptake of filoviral particles

HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 MMTV/c-Neu female mice) treatment inhibitsHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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