EI1 K805 another Wnt signaling inhibitor) produced

another Wnt signaling inhibitor) produced robust cardiac differentiation of hESCs/iPSCs in a xeno-free

2011 Jan 1

CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(O)=O

and triggered cell apoptosis

InChiKey: KVQOGDQTWWCZFX-UHFFFAOYSA-N

EI1 K805 another Wnt signaling inhibitor) producedEI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Product information CAS Number: 1418308 27 6 Molecular Weight: 390. 48 Formula: C23H26N4O2 Synonym: Ezh2 inhibitor EI 1 EI 1 Chemical Name: 6 cyano N [(4,6 dimethyl 2 oxo 1,2 dihydropyridin 3 yl)methyl] 1 (pentan 3 yl) 1H indole 4 carboxamide Smiles: CC1C=C(C)NC(=O)C=1CNC(=O)C1=CC(=CC2=C1C=CN2C(CC)CC)C#N InChiKey: PFHDWRIVDDIFRP