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Ozempic and Wegovy (semaglutide) and Mounjaro (tirzepatide) are GLP-1 receptor agonists that mimic the bodys natural GLP-1 hormone released from cells in the small intestine and in smaller quantities by the pancreas and central nervous system to stimulate insulin secretion, regulate appetite, inhibit glucagon secretion and delay gastric emptying

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In a genome-wide association study (GWAS) involving more than 140,000 individuals of European descent, uric acid receptors encoded by twenty-eight chromosomal genes were discovered to impact plasma uric acid levels