Pazopanib Catalog No.:M7809-10 Design and optimization of selective

Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases

InChiKey: QEKGSBZKRLHQSZ-VSIGASKDSA-N

MK-1775 was orally dosed to mice at 20 mg/Kg once per day

CAS Number: 2378801-85-3

Krishnaiah M

Pazopanib Catalog No.:M7809-10 Design and optimization of selectivePazopanib is an approved drug, is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR) 1, 2 and 3, c kit and platelet derived growth factor receptor (PDGF R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check for active clinical trials or closed clinical trials