Derazantinib - CAS# 1234356-69-4 6049 GSK2118436B ( Dabrafenib Mesylate )

GSK2118436B ( Dabrafenib Mesylate )

Smiles: CCOC(=O)C1C=CC(=CC=1)NC(=O)NCC1C=CC(=CC=1)N1C=CC=N1

Molecular Weight: 353

SB-334867 was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1

thiophenecarboxamide IKK-2 inhibitors

Derazantinib - CAS# 1234356-69-4 6049 GSK2118436B ( Dabrafenib Mesylate )Derazantinib, CAS No. 1234356 69 4, also known as ARQ 087, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR overexpressing tumor