NG25 ril (erbumine) Chemical Name: N-(3-cyano-4

Chemical Name: N-(3-cyano-4

hypertension

Chemical Name: 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy) quinazolin-4-amine

Smiles: OC1C=CC(/C=C/C(=O)CC(=O)/C=C/C2C=CC(O)=CC=2)=CC=1

2015 Nov 10

NG25 ril (erbumine) Chemical Name: N-(3-cyano-4NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38. NG 25 prevents TNF induced IKK phosphorylation and IB degradation in L929 cells. It inhibits secretion of IFN and IFN induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in