PKR-IN-1 KR-IN-1 The development of small molecule

The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases

CID 2011756 was the most potent of the inhibitors with a cellular EC50 of 10±0

31)32/h2-6

6(35):37758-69

Formula: C15H9NO2

PKR-IN-1 KR-IN-1 The development of small moleculeMitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency. Product information CAS Number: 1260075 17 9 Molecular Weight: 450. 55 Formula: C24H26N4O3S Chemical Name: N {4 [4 (cyclopropylmethyl)piperazine 1 carbonyl]phenyl}quinoline 8 sulfonamide Smiles: O=C(C1C=CC(=CC=1)NS(=O)(=O)C1=CC=CC2=CC=CN=C21)N1CCN(CC2CC2)CC1 InChiKey: XAYGBKHKBBXDAK UHFFFAOYSA N InChi: InChI=1S