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The presence of GLP-1R in the phylogenetically oldest parts of the brain but not in the cortex emphasizes that GLP-1 is involved in the regulation of vital functions like feeding and satiety (141)

Drug compounding is intended to address patient-specific medical needs, such as allergies, a need for a different dosage form, or when the FDA-approved drug is not medically appropriate to treat a particular patient

GLP-1 enhances glucose absorption and utilisation in muscle and adipose tissue by facilitating the translocation of GLUT4 to the cell membrane (Chang et al

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The role of tirzepatide in therapy will become more evident as more research is conducted