ADC Toxin Monomethyl auristatin F (MMAF) - CAS# 745017-94-1 Catalog No.:T60002-10S Formula: C18H17ClN2O3S

Formula: C18H17ClN2O3S

(2013) ACS Chem Biol

activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay

ACY-1215 was used at 1 µM final concentration in vitro and in cellular assays

InChi: InChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2

ADC Toxin Monomethyl auristatin F (MMAF) - CAS# 745017-94-1 Catalog No.:T60002-10S Formula: C18H17ClN2O3SMMAF (Monomethylauristatin F) , CAS No. 745017 94 1, is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN CD19A. Product information CAS Number: 745017 94 1 Molecular Weight: 731. 96 Formula: C39H65N5O8 Chemical Name: (S) 2 ((2R,3R) 3 ((S) 1 ((3R,4S,5S) 4 ((S) N,3 dimethyl 2 ((S) 3