GNF179 gotoxine mesylate EC50 = 280 nmol/L)

EC50 = 280 nmol/L)

is a potent and selective Wnt signaling pathway inhibitor discovered by a cell-based screening

(2012) Probe Reports from the NIH Molecular Libraries Program

PubMed Central PMCID: PMC6735670

Dominici FP

GNF179 gotoxine mesylate EC50 = 280 nmol/L)GNF179 is an antiparasitic drug. Product information CAS Number: 1261114 01 5 Molecular Weight: 427. 90 Formula: C22H23ClFN5O Synonym: GNF 179 GNF 179 Chemical Name: 2 amino 1 {3 [(4 chlorophenyl)amino] 2 (4 fluorophenyl) 8,8 dimethyl 5H,6H,7H,8H imidazo[1,2 a]pyrazin 7 yl}ethan 1 one Smiles: CC1(C)C2=NC(=C(NC3C=CC(Cl)=CC=3)N2CCN1C(=O)CN)C1C=CC(F)=CC=1 InChiKey: KFSKTWYDIHJITF UHFFFAOYSA N InChi: InChI=1S C22H23ClFN5O c1 22(2)21 27 19(14 3 7 16(24)8 4