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OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S HS Tariff Code: 382200

OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S HS Tariff Code: 382200

Name: OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S HS Tariff Code: 382200
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OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S HS Tariff Code: 382200OICR9429, CAS No. 1801787 56 3, is a potent and selective WD repeat containing protein 5 (WDR5) antagonist (Kd ~24 52 nM). It has >100 fold selectivity over other methyltransferases tested. It disrupts WDR5 interaction with peptide regions of MLL and Histone 3. OICR 9429 also disrupts the interaction of WDR5 with MLL1 and RbBP5 in cells with IC50 values below 1 M. Product information CAS Number: 1801787 56 3 Molecular Weight: 555. 59 Formula:

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Description

HS Tariff Code: 382200

130798-51-5

is a cell permeable and selective novel active-site KDM4A/KDM4B inhibitor with IC50 ~6

(Biochem Pharmacol

Cancer Discov

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