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Rigosertib - CAS# 592542-59-1 Catalog No.:M10594-10 with IC50 values between 0

Rigosertib - CAS# 592542-59-1 Catalog No.:M10594-10 with IC50 values between 0

Name: Rigosertib - CAS# 592542-59-1 Catalog No.:M10594-10 with IC50 values between 0
Brand: avramcheva.com
SKU: 46809848920
Price: 109.80 USD
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SKU: 46809848920

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Rigosertib - CAS# 592542-59-1 Catalog No.:M10594-10 with IC50 values between 0Rigosertib (ON 01910 sodium salt) is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity. Polo like kinase 1 inhibitor ON 01910. Na inhibits polo like kinase1 (Plk1), inducing selective G2 M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. This agent may exhibit synergistic antitumor activity in combination with other

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Description

with IC50 values between 0

Novitskiy SV

In late 2013

With the neutral lipid for the LNP is DOPE

Smiles: CC(C)OC(=O)[C@H](C)N[P@@](=O)(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@](C)(F)[C@@H]1O)OC1=CC=CC=C1

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