AG-490 Catalog No.:M7639-2 A novel small molecule inhibitor

A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma

3 h ours) acts in a DNA damage independent manner to activate nucleolar stress and RPA194 degradation

Molecular Weight: 328

It can also be synthetised

Long-Yun P

AG-490 Catalog No.:M7639-2 A novel small molecule inhibitorTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8