TAS-103 dihydrochloride l maleate Molecular Weight: 279

Molecular Weight: 279

Smiles: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@]1(OC(=O)C1C(C)(C)C1(C)C)C(=O)OCC#N

CAS Number: 63302-99-8

a third-generation

Sanapala KR

TAS-103 dihydrochloride l maleate Molecular Weight: 279TAS 103, also known as BMS 247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS 103 has been reported to be a potent topoisomerase II poison. TAS 103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0. 05). The combination with CDDP augmented the antitumor activity of TAS 103 (p<0. 05), indicating that CDDP is one of the most potent candidates