TAS0728 Size:10 mg solid 20 days) administers 15 min
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TAS0728 Size:10 mg solid 20 days) administers 15 minTAS0728 (TPC 107) is a potent, selective, orally active, irreversible and covalent binding inhibitor of HER2 (human epidermal growth factor receptor 2) with IC50 of 13 nM. TAS0728 inihibits BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2 with IC50 of 4. 9 nM, 8. 5 nM, 31 nM, 65 nM, 33 nM, 25 nM, 86 nM and 36 nM, respectively. TAS0728 shows antitumor activity. Product information CAS Number: 2088323 16 2 Molecular Weight: 504. 58 Formula:
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