WM 8014 inase inhibitor Antibiotic 230

Antibiotic 230

selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0

slows the rate of repolarisation (by 44±16 %) and causes a significant membrane potential depolarisation (from −83±1 mV to −71±5 mV)

InChiKey: ULFUJLFTRWWLPO-UHFFFAOYSA-N

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

WM 8014 inase inhibitor Antibiotic 230Potent and selective lysine acetyltransferase KAT6A and KAT6B inhibitor (IC50 values are 8 and 28 nM, respectively). Exhibits > 10 fold selectivity for KAT6A B over KAT7 and KAT5, and no significant activity against KAT8, KAT2A 2B, and KAT3A B. Induces cell cycle arrest in G1 G0 in MEFs and inhibits proliferation of lymphoma cells in vitro. Cell permeant. Suitable for use in vitro. Product information CAS Number: 2055397 18 5 Molecular Weight: 384. 42