Laropiprant sartan 23)19-10-9-14(12-19)5-8-16(20)17-21/h3-10

23)19-10-9-14(12-19)5-8-16(20)17-21/h3-10

Mice treated with TAS-116 (10 mg/kg and 15 mg/kg

Smiles: NC1=CC(F)=CC=C1NC(=O)/C=C/C1C=NN(C/C=C/C2C=CC=CC=2)C=1

is a n orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity

CAS Number: 1415560-64-3

Laropiprant sartan 23)19-10-9-14(12-19)5-8-16(20)17-21/h3-10Laropiprant, aslo known as MK 0524, was a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold, due to increases in side effects with no cardiovascular benefit. Laropiprant itself has no cholesterol lowering effect, but it reduces facial flushes induced by niacin. Laropiprant acts as a selective DP1 antagonist, reducing the vasodilation. Product information CAS Number: 571170 77 9 Molecular Weight: