GBT-440 - CAS# 1446321-46-5 0042 2014 Jun 1
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GBT-440 - CAS# 1446321-46-5 0042 2014 Jun 1GBT 440, CAS No. 1446321 46 5, is a hemoglobin S allosteric modulator. GBT440 Inhibits Sickling of Sickle Cell Trait Blood Under In Vitro Conditions Mimicking Strenuous Exercise. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half life in a murine model of sickle cell disease. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half life in a murine model of sickle cell disease. Product
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