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AUY-922 - CAS# 747412-49-3 Catalog No.:M6487-10 69(5):1916-23

AUY-922 - CAS# 747412-49-3 Catalog No.:M6487-10 69(5):1916-23

Name: AUY-922 - CAS# 747412-49-3 Catalog No.:M6487-10 69(5):1916-23
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AUY-922 - CAS# 747412-49-3 Catalog No.:M6487-10 69(5):1916-23AUY 922, also known as Luminespib, NVP AUY922, VER52296, CAS No. 747412 49 3, is a derivative of 4, 5 diarylisoxazole and a third generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY 922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock

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Description

69(5):1916-23

483(7390):479-83

Epub 2016 Oct 24

This Wnt-dependent culture system should provide a platform for complete replacement of growth factors with chemical compounds

CH223191 (0

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