DK419 - CAS# 2102672-22-8 Catalog No.:M6956-10 Combined inhibition of EGFR and

Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells

RIPK2 inhibitor-1

Bacteriochlorophyll from Rhodopseudomonas sphaeroides

InChi: InChI=1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12

IL-1b and A20

DK419 - CAS# 2102672-22-8 Catalog No.:M6956-10 Combined inhibition of EGFR andDK419, CAS No. 2102672 22 8, is a potent inhibitor of Wnt catenin signaling and colorectal cancer growth. DK419 inhibited Wnt catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally. Product information CAS Number: 2102672 22 8