Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips Checkpoint kinase 2 encoded by

Checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor

Mutations in this gene have been associated with geroderma osteodysplastica

They are plasma membrane proteins containing seven epidermal growth factor-like repeats

KCNC1 encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes

The related mouse gene is expressed only in oocytes

Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips Checkpoint kinase 2 encoded bySFXN4 encodes a member of the sideroflexin family. The sideroflexin 4 is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene.