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BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide

BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide

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BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamideBIBW2992 (Afatinib), CAS No. 439081 18 2, is a highly potent and selective irreversible EGFR inhibitor, inhibiting EGFRwt, EGFRL858R, EGFRL858R T790M and HER2 with IC50 of 0. 5 nM, 0. 4 nM, 10 nM, 14 nM, respectively. BIBW2992 suppresses transformation in isogenic cell based assays, inhibits survival of cancer cell lines, exhibits potent effects on both EGFR and HER2 phosphorylation, and induces tumor regression in xenograft and transgenic lung cancer

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Description

4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide

(2005) Cardiovasc Drug Rev

These culture conditions do not include xenobiotic supplements

Formula: C19H17NO3

CAS Number: 1884220-36-3

BIBW2992(Afatinib) - EGFR Inhibitor. CAS# 439081-18-2 Catalog No.:M60065-10S 4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamideBIBW2992 (Afatinib), CAS No. 439081 18 2, is a highly potent and selective irreversible EGFR inhibitor, inhibiting EGFRwt, EGFRL858R, EGFRL858R T790M and HER2 with IC50 of 0. 5 nM, 0. 4 nM, 10 nM, 14 nM, respectively. BIBW2992 suppresses transformation in isogenic cell based assays, inhibits survival of cancer cell lines, exhibits potent effects on both EGFR and HER2 phosphorylation, and induces tumor regression in xenograft and transgenic lung cancer

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