Vortioxetine hydrobromide Catalog No.:M10128-10 Dual role of isocitratelyase 1

Dual role of isocitratelyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis

CAS Number: 1228690-19-4

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Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation

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Vortioxetine hydrobromide Catalog No.:M10128-10 Dual role of isocitratelyase 1Vortioxetine, also known as Lu AA21004, is an atypical antidepressant, and was approved in 2013 by the U. S. FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so called "serotonin modulator and stimulator." It has been shown to possess the following pharmacological actions: Serotonin transporter (SERT) blocker (i. e. serotonin reuptake inhibitor (SRI)) Ki (binding affinity) = 1. 6 nM, IC50 = 5. 4 nM; Norepinephrine