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FRAX597 Catalog No.:M9936-10 (R)-MG132 is a potent

SKU: 56284967886

4.5
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FRAX597 Catalog No.:M9936-10 (R)-MG132 is a potentFRAX597 is a potent and selective inhibitor of the p21 activated kinases. FRAX597 inhibits tumorigenesis of neurofibromatosis type 2 (NF2) associated Schwannomas. FRAX597 inhibits the proliferation of NF2 deficient schwannoma cells in culture and displayed potent anti tumor activity in vivo, impairing schwannoma development in an orthotopic model of NF2. These studies identify a novel class of orally available ATP competitive Group I PAK inhibitors

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(R)-MG132 is a potent

Smiles: CC(C)C1=CC(=CC(C(C)C)=C1CC(=O)NS(=O)(=O)OC1C(=CC=CC=1C(C)C)C(C)C)C(C)C

3]oxazol-7-yl]-3

11-dimethyl-6

1191911-26-8

FRAX597 Catalog No.:M9936-10 (R)-MG132 is a potentFRAX597 is a potent and selective inhibitor of the p21 activated kinases. FRAX597 inhibits tumorigenesis of neurofibromatosis type 2 (NF2) associated Schwannomas. FRAX597 inhibits the proliferation of NF2 deficient schwannoma cells in culture and displayed potent anti tumor activity in vivo, impairing schwannoma development in an orthotopic model of NF2. These studies identify a novel class of orally available ATP competitive Group I PAK inhibitors

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