SCH-1473759 pferide Kozłowska E

Kozłowska E

the cardiac function of Nedocromil-treated diabetic mice remains significantly impaired when compared with normal mice

InChi: InChI=1S/C19H19N/c1-20-11-10-18-16-8-4-2-6-14(16)12-15-7-3-5-9-17(15)19(18)13-20/h2-9H

5 sodium channel protein expression as dose-dependent manner in C2C12 cells

PF 01367338 phosphate

SCH-1473759 pferide Kozłowska ESCH 1473759 is a potent and selective Aurora A B inhibitor with IC50 sub nanomolar. SCH 1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH 1473759 demonstrated potent mechanism based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. Product