DMH-1 - CAS# 1206711-16-1 0197 indicating that the drug directly

indicating that the drug directly interacts with tubulin at the colchicine-binding site

Each library comes with a compound list in Excel sheet

It suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation

Smiles: CC(C)C(=O)NC(C1=CC=CO1)C1=CC=C2C=CC=NC2=C1O

34(1):58-61

DMH-1 - CAS# 1206711-16-1 0197 indicating that the drug directlyDMH 1, CAS No. 1206711 16 1, is a second generation small molecule BMP inhibitor based on dorsomorphin. DMH 1 effectively inhibits the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM). Treatment with DMH1 reduced lung metastasis and the tumors were less proliferative and more apoptotic. In the surrounding tumor microenvironment, treatment with DMH1 altered fibroblasts, lymphatic vessels and macrophages to be less tumor promoting. These