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AMG 232 Catalog No.:M8600-10 is a potent and selective

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AMG 232 Catalog No.:M8600-10 is a potent and selectiveAMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0. 045 nM, SJSA 1 EdU IC50 = 9. 1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA 1 osteosarcoma xenograft model (ED50 = 9. 1 mg kg). AMG232 is currently under clinical development. Product information CAS Number: 1352066 68 2 Molecular Weight: 568. 55 Formula: C28H35Cl2NO5S Synonym: AMG232 AMG 232 Chemical Name: 2 [(3R,5R,6S) 5 (3 chlorophenyl) 6 (4

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Description

is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production

Asaraldehyde down-regulates C/EBPβ

PubMed PMID: 26185454

InChi: InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12

Formula: C19H14N2O4

AMG 232 Catalog No.:M8600-10 is a potent and selectiveAMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0. 045 nM, SJSA 1 EdU IC50 = 9. 1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA 1 osteosarcoma xenograft model (ED50 = 9. 1 mg kg). AMG232 is currently under clinical development. Product information CAS Number: 1352066 68 2 Molecular Weight: 568. 55 Formula: C28H35Cl2NO5S Synonym: AMG232 AMG 232 Chemical Name: 2 [(3R,5R,6S) 5 (3 chlorophenyl) 6 (4

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