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CCT241533 Hydrochloride - CAS# 1431697-96-9 ropylthiouracil BCIP(BCIP p-toluidine salt

SKU: 58206381005

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CCT241533 Hydrochloride - CAS# 1431697-96-9 ropylthiouracil BCIP(BCIP p-toluidine saltCCT 241533 dihydrochloride is a potent Chk2 inhibitor (IC50 = 3 nM). It shows >63 fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. CCT 241533 dihydrochloride inhibits Chk2 activation in response to etoposide induced DNA damage in HT29 cells and blocks ionizing radiation induced apoptosis of mouse thymocytes. Product information CAS Number: 1431697 96 9 Molecular Weight: 478. 94 Formula: C23H28ClFN4O4 Synonym: CCT 241533

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Description

BCIP(BCIP p-toluidine salt

producing organism and fermentation

and 50 mg/kg for 18 months (groups O

and 5-HT7 receptors (pKi = 7

PD173074 treatment potently reduces viability of FGFR3-expressing KMS11 and KMS18 cells with IC50 of <20 nM

CCT241533 Hydrochloride - CAS# 1431697-96-9 ropylthiouracil BCIP(BCIP p-toluidine saltCCT 241533 dihydrochloride is a potent Chk2 inhibitor (IC50 = 3 nM). It shows >63 fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. CCT 241533 dihydrochloride inhibits Chk2 activation in response to etoposide induced DNA damage in HT29 cells and blocks ionizing radiation induced apoptosis of mouse thymocytes. Product information CAS Number: 1431697 96 9 Molecular Weight: 478. 94 Formula: C23H28ClFN4O4 Synonym: CCT 241533

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