CBB1007 trihydrochloride lioxanthin 8-1 Chemical Name: N-[1-(cyclopropylmethoxy)-4-hydroxy-2-oxo- 1

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CBB1007 trihydrochloride lioxanthin 8-1 Chemical Name: N-[1-(cyclopropylmethoxy)-4-hydroxy-2-oxo- 1CBB1007 is a potent and selective Lysine specific demethylase 1 (LSD1) inhibitor. CBB1007 trihydrochloride is a cell permeable amidino guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5. 27 M for hLSD1). IC50 Value: 5. 27 uM Target: hLSD1 CBB1007 efficiently can block LSD1 mediated demethylation of H3K4Me2 and H3K4Me (IC50 5 M) with no effect on H3K4Me3 and H3K9Me2, and LSD2 and JARID1A

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