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VLX1570 - CAS# 1431280-51-1 size:10mg solid Virshup IH

SKU: 62974999022

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VLX1570 - CAS# 1431280-51-1 size:10mg solid Virshup IHVLX1570, CAS No. 1431280 51 1, is an inhibitor of the 19S proteasome specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with apoptosis inducing and antineoplastic activities. Upon administration, VLX1570 specifically binds to both USP14 and UCHL5, thereby blocking their deubiquitylating activity. This blocks the ubiquitin proteasome degradation pathway, prevents the degradation of defective proteins, and leads to an accumulation of poly

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Description

Virshup IH

Cambendazole

NAALADase inhibitor

Nifedipine and AP-3 on primary cultures of cerebellar granule cells in an oxygen-glucose deprivation model

348(2):167-76

VLX1570 - CAS# 1431280-51-1 size:10mg solid Virshup IHVLX1570, CAS No. 1431280 51 1, is an inhibitor of the 19S proteasome specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with apoptosis inducing and antineoplastic activities. Upon administration, VLX1570 specifically binds to both USP14 and UCHL5, thereby blocking their deubiquitylating activity. This blocks the ubiquitin proteasome degradation pathway, prevents the degradation of defective proteins, and leads to an accumulation of poly

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