Diphylline ntin) PubMed Central PMCID: PMC4264672

PubMed Central PMCID: PMC4264672

Chemical Name: N-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide

2414909-94-5

5-trien-7-yl]methyl}((²H₃)methyl)amino)propyl]-7

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(=O)OCCOCCNC(=O)CO/N=C1\CCC(C)(C)C(C=C/C(/C)=C/C=C/C(/C)=C/C(O)=O)=C\1C |t:41|

Diphylline ntin) PubMed Central PMCID: PMC4264672Dyphylline is a phosphodiesterase inhibitor used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects. It also acts as an adenosine receptor antagonist. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other