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CH223191 - CAS# 301326-22-7 size:10mg solid Smiles: CN(CC1C=CC=CC=1)C1=CC2OC(=O)C(=CC=2C=C1)C(O)=O

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CH223191 - CAS# 301326-22-7 size:10mg solid Smiles: CN(CC1C=CC=CC=1)C1=CC2OC(=O)C(=CC=2C=C1)C(O)=OCH223191, CAS No. 301326 22 7, is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. CH223191 can prevent 2, 3, 7, 8 TCDD induced toxicity by antagonizing the aryl hydrocarbon receptor. 2, 3, 7, 8 Tetrachlorodibenzo p dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD induced AhR

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Description

Smiles: CN(CC1C=CC=CC=1)C1=CC2OC(=O)C(=CC=2C=C1)C(O)=O

also known as JNK Inhibitor XVI

(2014) Nat Commun

In recent publication CI994 could also epigenetically prime the hippocampal transcriptome for reinstated neuroplasticity and lead to increased neuroplasticity during memory extinction

HCQ treatment has been shown to cause increased apoptosis

CH223191 - CAS# 301326-22-7 size:10mg solid Smiles: CN(CC1C=CC=CC=1)C1=CC2OC(=O)C(=CC=2C=C1)C(O)=OCH223191, CAS No. 301326 22 7, is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. CH223191 can prevent 2, 3, 7, 8 TCDD induced toxicity by antagonizing the aryl hydrocarbon receptor. 2, 3, 7, 8 Tetrachlorodibenzo p dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD induced AhR

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