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SJF 8240 nepazide Maleate Epub 2008 Jul 4

SKU: 72890356941

4.4
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SJF 8240 nepazide Maleate Epub 2008 Jul 4c MET PROTACDegrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel Lindau (VHL) recruiting ligand. Degrades c MET within 6 hours in vitro. Inhibits agonist driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66. 7 nM). Also degrades exon 14 deleted c MET in Hs746T cells. Product information CAS Number: 2230821 68 6 Molecular Weight: 1106. 24 Formula: C58H65F2N7O11S Synonym: SJF 8240

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Description

Epub 2008 Jul 4

Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma

Molecular Weight: 331

Chemical Name: 5-((1-(2

CAS Number: 1223403-58-4

SJF 8240 nepazide Maleate Epub 2008 Jul 4c MET PROTACDegrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel Lindau (VHL) recruiting ligand. Degrades c MET within 6 hours in vitro. Inhibits agonist driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66. 7 nM). Also degrades exon 14 deleted c MET in Hs746T cells. Product information CAS Number: 2230821 68 6 Molecular Weight: 1106. 24 Formula: C58H65F2N7O11S Synonym: SJF 8240

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