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A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Brain Penetrant LRRK2 Inhibitorn (2012)

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A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Brain Penetrant LRRK2 Inhibitorn (2012)A769662, CAS No. 844499 71 4, is a potent and selective small molecule activator of AMP activated protein kinase (AMPK). It induces allosteric activation of AMPK and inhibition of dephosphorylation of AMPK on Thr 172, similar to the effects of AMP. The activation of AMPK inhibits mTOR signaling, which is a positive effector of cell growth and survival. A769662 stimulated partially purified rat liver AMPK with an EC50 of 0. 8 M and inhibited fatty acid

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Description

Brain Penetrant LRRK2 Inhibitorn (2012) ACS Med

4-oxadiazol-5-yl)piperidin-1-yl)methanone

When PAI-039 is dosed in a treatment paradigm 4 h after stable arterial and venous thrombosis

Epub 2009 Oct 6

Molecular Weight: 618

A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Brain Penetrant LRRK2 Inhibitorn (2012)A769662, CAS No. 844499 71 4, is a potent and selective small molecule activator of AMP activated protein kinase (AMPK). It induces allosteric activation of AMPK and inhibition of dephosphorylation of AMPK on Thr 172, similar to the effects of AMP. The activation of AMPK inhibits mTOR signaling, which is a positive effector of cell growth and survival. A769662 stimulated partially purified rat liver AMPK with an EC50 of 0. 8 M and inhibited fatty acid

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