SCH900776 Size:Solid 10 mg also known as DMBX-A

also known as DMBX-A

PubMed PMID: 30101119

is a dual antagonist of the A2aR and A2bR adenosine receptors

5-e]azepin-4-yl)acetamide

InChi: InChI=1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30

SCH900776 Size:Solid 10 mg also known as DMBX-ASCH900776, also known as MK 8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1 dependent cell cycle arrest in the S and G2 M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA damaging effects of ionizing