Ifosfamide - CAS# 3778-73-2 anthine which is significantly lower than

which is significantly lower than that of 3-AP (Triapine

InChi: InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12

including DP1 (>1000-fold selective)

SB203580 also inhibits the activity of PDK1 in a dose-dependent manner with an IC50 in the 3–10 μm range

4-diazepan-1-yl]quinazolin-4-amine

Ifosfamide - CAS# 3778-73-2 anthine which is significantly lower thanIfosfamide is a synthetic analogue of the nitrogen mustard cyclophosphamide with antineoplastic activity. Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Product information CAS Number: 3778 73 2