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[0040] In step 3), the fully-protected fragment of PEG-PEG--Glu-Octadecanedioic Acid is prepared using 2-CTC chloride resin, wherein cleavage is performed with 1-2% TFA/CH 2 Cl 2 or 20% TFE/CH 2 Cl 2

Patients receive ongoing medical oversight throughout the program, including regular check-ins to monitor progress and response to treatment

Epub 2019 Jan 8

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(Sodhi et al., JAMA 2023) Stay hydrated take frequent small sips of water or sugar-free squash throughout the day Temporarily switch to low-fibre foods: white bread, plain crackers, white rice, or pasta Eat small, frequent meals rather than large ones Avoid spicy, fatty, or very rich foods Ask your pharmacist about anti-diarrhoea medication let them know you are taking semaglutide See a doctor if it lasts more than 7 days, or if there is blood in your stools Constipation Because semaglutide slows down digestion, some people find that their bowels become sluggish