Y15 481585 Smiles: CN(C)C1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O

Smiles: CN(C)C1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O

Combining PDMP and GNF-2 eliminated transplanted-CML-T315I-mutants in vivo and dose dependently sensitized primary cells from CML T315I patients to GNF-2-induced proliferation inhibition and apoptosis

FH535 inhibits PPARγ and PPARδ transactivation in HCT116 cells

InChiKey: AXNUEXXEQGQWPA-UHFFFAOYSA-N

5-dihydro-1H-pyrazol-1-yl)benzoic acid

Y15 481585 Smiles: CN(C)C1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1OY15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylation inhibitor, blocking phosphorylation of Y397 with an IC50 value of about 1 M. Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics. Y15 was shown to decrease cancer growth in vitro and in vivo. Product information CAS Number: 4506 66 5 Molecular Weight: 174. 63 Formula: C6H11ClN4 Synonym: