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AZD2858 46040 5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrate

SKU: 8316342799

4.1
USD90.00 USD132.00

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AZD2858 46040 5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrateAZD2858 is a potent and GSK 3 inhibitor with an IC50 of 68 nM. AZD 2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt signaling pathway. AZD2858 has a substantial impact on fracture healing. The fractures healed with a bony callus without an obvious endochondral component, suggesting that AZD2858 drives mesenchymal cells into the osteoblastic pathway. Product information CAS Number: 486424 20 8 Molecular Weight: 453. 52 Formula:

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Description

5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrate

which is comparable with the response seen with activated wt mALK

Solubility: DMSO: 90 mg/mL(189

and 100 mg/kg) elicits a dose-dependent decrease in serum human GH levels

InChi: InChI=1S/C14H20Br2N2

AZD2858 46040 5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrateAZD2858 is a potent and GSK 3 inhibitor with an IC50 of 68 nM. AZD 2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt signaling pathway. AZD2858 has a substantial impact on fracture healing. The fractures healed with a bony callus without an obvious endochondral component, suggesting that AZD2858 drives mesenchymal cells into the osteoblastic pathway. Product information CAS Number: 486424 20 8 Molecular Weight: 453. 52 Formula:

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