Oxymetazoline Hydrochloride Catalog No.:M10842-10 2-b]pyridin]-3-ol

2-b]pyridin]-3-ol

61(15):6705-6723

PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml)

and 9% for doses of 3

wtRyR1-HEK 293 pretreated with KB-R7943 (10 μM

Oxymetazoline Hydrochloride Catalog No.:M10842-10 2-b]pyridin]-3-olOxymetazoline is a selective 1 adrenergic receptor agonist and 2 adrenergic receptor partial agonist. It is a topical decongestant, used in the form of oxymetazoline hydrochloride in products such as Afrin, Dristan, Nasivin, Nezeril, Nostrilla, Logicin, Vicks Sinex, Visine L. R., Sudafed OM, Zicam, SinuFrin and Mucinex Sinus Max. It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961. Oxymetazoline is generally available as