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The onset of cartilage destruction is due to mechanical stress, which either directly damages chondrocytes or activates them to produce abnormal levels of MMPs and reactive oxygen species (ROS) responsible for cartilage breakdown and the release of microcrystals, osteochondral fragments, and products of ECM degradation into the joint cavity

Most people start to notice improvements in joint comfort and skin texture after four to eight weeks of consistent use

Li Z, Li S, Li K, Jiang X, Zhang J, Liu H

Eczema, also known as atopic dermatitis, is a chronic, or ongoing, disease

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