R428 - CAS# 1037624-75-1 Catalog No.:M10306-2 CAS Number: 262438-43-7

CAS Number: 262438-43-7

It displays excitation/emission maxima of 543/572 nm

10(485):eaak9916

para-iodoHoechst 33258 is part of a family of blue fluorescent dyes used to stain DNA

SW044248 (10 μM) rapidly activates the integrated stress response through kinases GCN2 and PKR

R428 - CAS# 1037624-75-1 Catalog No.:M10306-2 CAS Number: 262438-43-7Bemcentinib, also known as BGB 324 or R428, is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl dependent events, including Akt