Pirfenidone - CAS# 53179-13-8 0207 InChiKey: UYPYRKYUKCHHIB-UHFFFAOYSA-N

InChiKey: UYPYRKYUKCHHIB-UHFFFAOYSA-N

2/6/24 hours) dramatically decreases the cyclin D-1 mRNA levels in a time-dependent manner in primary HMVEC

specifically inhibits this interaction by binding to c-Myc

InChiKey: LLJJDLHGZUOMQP-UHFFFAOYSA-N

18(5):415-420

Pirfenidone - CAS# 53179-13-8 0207 InChiKey: UYPYRKYUKCHHIB-UHFFFAOYSA-NPirfenidone, CAS No. 53179 13 8, is an anti fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well established antifibrotic and anti inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell based studies have shown that pirfenidone reduces fibroblast