CCT129202 - CAS# 942947-93-5 10575 InChi: InChI=1S/C31H44N2O5S

InChi: InChI=1S/C31H44N2O5S

8-tetramethyl-3

SCH-527123 treatment decreased tumor growth and microvessel density when compared with vehicle-treated tumors

a serine/threonine protein kinase overexpressed in certain types of cancer cells

Constant illumination can activate each molecule of talaporfin many times

CCT129202 - CAS# 942947-93-5 10575 InChi: InChI=1S/C31H44N2O5SCCT129202 is an inhibitor of Aurora kinase activity and displays a favorable antineoplastic effect in preclinical studies. CCT129202 significantly reversed ABCB1 and ABCG2 mediated MDR in vitro, in vivo and ex vivo by inhibiting the function of their transporters and enhanced the eradication of cancer stem like cells by chemotherapeutic agents. CCT129202 may be a candidate as MDR reversal agent for antineoplastic combination therapy and merits further