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GO-6976 - CAS# 136194-77-9 Catalog No.:M6821-10 Prevention of the expression of

GO-6976 - CAS# 136194-77-9 Catalog No.:M6821-10 Prevention of the expression of

Name: GO-6976 - CAS# 136194-77-9 Catalog No.:M6821-10 Prevention of the expression of
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GO-6976 - CAS# 136194-77-9 Catalog No.:M6821-10 Prevention of the expression ofGO 6976, CAS No. 136194 77 9, also known as PD 406976, is a potent inhibitor of neurotrophin receptor intrinsic tyrosine kinase. GO 6976 blocked neurotrophin induced signaling and autophosphorylation of neurotrophin specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1 1 trk9 cells. Product information CAS Number: 136194 77 9 Molecular Weight: 378. 43 Formula: C24H18N4O Synonym: PD406976 Chemical Name: 3 (13 methyl

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Description

Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth

p110β (IC50=0

4 μM for KDM4A and 9

Petr Olegovich

MK-1775 was orally dosed to mice at 20 mg/Kg once per day

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