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GAPDH (glyceraldehyde 3-phosphate dehydrogenase) served as a loading control for total protein, while Histone-H3 was used for nuclear extracts

The enzyme plays a more crucial role of inhibiting lipid peroxidation process, and therefore protects cells from oxidative stress.25 According to Morn and Cortzar, there are at least eight GPx enzymes in human, GPx1GPx8

In particular, inhibitors or activators targeting cellular components, as well as biomolecules, enzymes, and nutrients, can stimulate apoptotic signaling pathways

This is attributed to the shame and impaired self-esteem caused by hair loss, which can affect appearance (54, 55)

Targeting TLR/NF-kB and MAPK signaling TIPE2 TIPE2 (tumor necrosis factor- induced protein 8 (TNFAIP8)-like 2) has emerged as a complex regulator of immune responses in tumor progression and immune suppression.TIPE2 belongs to the TNFAIP8 protein family, which consists of four classes: TIPE, TIPE1, TIPE2, and TIPE3 [140]