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Trimethylamine N-oxide - CAS# 1184-78-7 0090 Epub 2013 Mar 28

Trimethylamine N-oxide - CAS# 1184-78-7 0090 Epub 2013 Mar 28

Name: Trimethylamine N-oxide - CAS# 1184-78-7 0090 Epub 2013 Mar 28
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Trimethylamine N-oxide - CAS# 1184-78-7 0090 Epub 2013 Mar 28Trimethylamine N oxide, CAS No. 1184 78 7, is a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients. Trimethylamine N oxide induces inflammation by activating the ROS NLRP3 inflammasome. Trimethylamine N oxide also accelerates fibroblast myofibroblast differentiation and induces cardiac fibrosis by activating the TGF smad2 signaling pathway. Product information CAS Number: 1184 78 7 Molecular Weight: 75.

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Description

Epub 2013 Mar 28

PF-2545920

Inhibitory effect of TAS-301

InChi: InChI=1S/C17H20F2N4O3S/c1-27(24

and DNA-binding

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