SMER3 - SCF family E3 Ubiquitin Ligase Inhibitor. CAS# 67200-34-4 size:2 mg solid Formula: C23H21ClN2O5

Formula: C23H21ClN2O5

Mol Cell Biochem

17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H

The UK5099 treated cells show significantly higher proportion of side population fraction and express higher levels of stemness markers Oct3/4 and Nanog

GSK-J4 could significant reduce LPS-induced pro-inflammatory cytokine production in primary human macrophages (IC50 ~9 μM for the inhibition of TNFα release)

SMER3 - SCF family E3 Ubiquitin Ligase Inhibitor. CAS# 67200-34-4 size:2 mg solid Formula: C23H21ClN2O5SMER3, CAS No. 67200 34 4, is a small molecule enhancer of rapamycin (SMER). It is also a specific inhibitor of Ubiquitin E3 ligase. Product information CAS Number: 67200 34 4 Molecular Weight: 224. 18 Formula: C11H4N4O2 Chemical Name: 9H indeno[1,2 b][1,2,5]oxadiazolo[3,4 e]pyrazin 9 one Smiles: O=C1C2=NC3=NON=C3N=C2C2=CC=CC=C21 InChiKey: SFSSAKVWCKFRHE UHFFFAOYSA N InChi: InChI=1S C11H4N4O2 c16 9 6 4 2 1 3 5(6)7 8(9)13 11 10(12 7)14 17 15 11 h1 4H